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Researchers at MIT have discovered a method for reversing hearing loss that may be as simple as having Lasik 

You might find hearing loss to be a frustrating aspect of growing older, whether you are the one who is experiencing it or know someone who does. Dementia has been found to be associated with tinnitus, a sense of isolation caused by hearing loss. That is one of the reasons why so many people are interested in research into ways to reverse hearing loss. Researchers affiliated with an MIT spinoff believe they have discovered a solution to this problem.

Researchers at MIT have discovered a method of reversing hearing loss

Frequency Therapeutics, a spinout from MIT, is investigating novel strategies for reversing hearing loss and is currently recruiting employees. Patients will not benefit from hearing aids or implants, on the other hand. Instead, a new type of regenerative therapy, developed by a biotech company, is intended to repair the tiny hair cells that allow us to hear by restoring their function.

In addition to aging, hair cells are also susceptible to death if they are exposed to loud noises or drugs. Hearing loss can occur in any of these situations because the ears rely on minute hairs to detect sound, and any of these circumstances can result in hearing loss. However, it is possible that Frequency Therapeutics has discovered a way to repair the damage.

It has been conducting clinical trials of a regenerative therapy in which small molecules are used to program progenitor cells, which is currently in phase 2. These cells are the descendants of stem cells. They are found in the inner ear and are responsible for the production of the tiny hair cells that are required for normal hearing function. So the cells are better equipped to restore hearing loss by replacing the hairs that were responsible for its development in the first place.

It's an intriguing move, and one that, if they keep working on it, could bear fruit in the future. Up to this point, the company has experienced exceptional results in tests of speech perception. "The primary goal of hearing improvement is to improve speech perception," says Chris Loose, Ph.D., co-founder and Chief Scientific Officer of Frequency.

Maturing and growing

To date, Frequency Therapeutics has administered doses of its regenerative therapy to more than 200 patients. Hearing loss has been reversed in three of Frequency's clinical trials, which were conducted in the United Kingdom. One study, on the other hand, found no evidence of improvement. Each of the four tests was created to measure improvements in the ability to perceive speech.

The 124-person trial has been reopened at the request of the company, which is now appealing the decision. It expects to have preliminary results available by the beginning of next year at the earliest. If the trial is a success, it is possible that the regenerative therapy will be tested on a larger number of people. It still has a long way to go before it can be sold on the official market place. Preliminary results, on the other hand, appear to be encouraging for those who wish to reverse their hearing loss.

Furthermore, the scientists believe that as the program matures and expands, it will become much easier to administer as a result.

According to Jeff Karp, an affiliate faculty member at Harvard-MIT Health Sciences and Technology, "I wouldn't be surprised if, in ten or fifteen years, as a result of the resources invested in this space and the incredible science being conducted, we can get to a point where reversing hearing loss is comparable to Lasik surgery, where you're in and out in an hour or two and can completely restore your vision," said in a statement.

If this is the case, it is possible that we will be able to completely reverse hearing loss in the future. This alone has the potential to have a significant impact on the society in which we live.

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