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 How The Leading Covid 19 Vaccines Work

Covid-19 Vaccine


What is Vaccine 


A Vaccine is a biological preparation that provides active sufficient immunity to a specific infectious disease.


The United States and United Kingdom and other countries including Russia, China, and India, are investing in more traditional approaches, like inactivated coronavirus vaccines. Irrespective of the techniques, together they have the potential to create multiple lines of defense against SARS-CoV-2.


Science expert Correspondent Jon Cohen explains how each of these vaccines can protect us from severe illness —and what understanding the details of our immune responses could mean for the future of human trials. There is an evidence that current vaccines are effective against SARS-CoV-2 variants.



Principle On How the Covid 19 Vaccine Works?



1. The First Process is Pfizer/BioNTech


Pfizer / BioNTech use a new approach to making vaccines . This process was chosen for a pandemic vaccine years ago because it's one that lends itself to quick turnaround. All what is needed is the genetic sequence of the virus causing the pandemic. Vaccine makers do not even need the virus itself -- just the sequence.


In this case, BioNTech expert used a little piece of genetic material coding for a piece of the spike protein -- those studs that cover the surface of the coronavirus and the source of its name. Corona means "crown.


Clinical trials proofs that Pfizer's vaccine was 95% effective in preventing symptomatic infections. Pfizer vaccine is active  to show that the vaccine can prevent all infections, including those that do not cause symptoms. Clinical trials has also been testing it vaccine against some of the worrying new variants of coronavirus. Studies has proof that  the vaccine can protect against variants causing concern in South Africa and the UK. Pfizer's vaccine must be kept at ultra cold temperatures of about minus 100 degrees Fahrenheit (minus 75 degrees Celsius), which means special equipment is needed to transport and store this vaccine.


In December Pfizer's is being delivered to millions of people in the United state  and United Kingdom. The United state government has deiced to buy 300 million doses of Pfizer's coronavirus vaccine. 



2 . The Second Process is RNA


RNA are temporary vital information instructing cells to make one viral protein temporarily," Shane Crotty, a virologist at the La Jolla Institute for Immunology.

RNA is a genetic code that cells can  use to make a protein. In the case of this vaccine, the mRNA instructs the muscle cells in the arm to make a particular piece of the virus's spike protein called the receptor binding domain, the immune system sees it, recognizes it as foreign and is prepared to attack when actual infection occurs.



3.  The Third Process is MRNA 


MRNA is very fragile so it's encased in lipid nano particles -- a coating of a buttery substance that can melt at room temperature. 

Adverse effects from vaccination are not common and  are usually mild. The adverse -effect include fever and headache, although a very few people have experienced allergic reactions to the vaccine.

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